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Understanding the role of gene duplications in cereals using CRISPR
Targeted mutagenesis is a important part in our research to unravel the role of key regulatory genes in plant development. Within this project, we will CRISPR-Cas in barley on key developmental genes to understand their role in sh ...
Supervisor: Wilma van Esse
Department: Molecular Biology, Laboratory of |
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SCHIZORIZA: tissues with multiple personalities
Asymmetric cell division is a fundamental and universal mechanism for generating diversity and pattern in multicellular organisms. SCHIZORIZA (SCZ), a transcriptional co-factor controls the separation of cell fate in a set of stem ...
Supervisor: Renze Heidstra
Department: Molecular Biology, Laboratory of |
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CRISPR-Cas in plant development
Recent advances with the RNA-mediated CRISPR-Cas systems have dramatically transformed our ability to specifically modify intact genomes of diverse cells and organisms. The CRISPR–Cas system has proven to be an efficient, simple, ...
Supervisor: Dr. Ir. R Heidstra
Department: Molecular Biology, Laboratory of |
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Stem cell maintenance in the Arabidopsis root
All tissues are ultimately generates by the activity of stem cells. In the root of the model plant Arabidopsis a group of stem cells surround a mitotically inactive organizer, named Quiescent Center (QC). Both the activities of th ...
Supervisor: Renze Heidstra
Department: Molecular Biology, Laboratory of |
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Regeneration genes
Introduction of transgenes in plants has been a force in molecular biology and biotechnology for decades. Agrobacterium tumefaciens is generally used as a vehicle to introduce genetic material in the plant cell. Unfortunately, not ...
Supervisor: Dr. Ir. R Heidstra and Dr H Nijveen (BIF)
Department: Molecular Biology, Laboratory of |
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Role of Ubiquitin Proteasome System in Gamete Interaction.
Protein ubiquitination is one mode of post-translational modification mechanism essential in several biological processes. It involves covalent attachments of ubiquitin to the lysine residue of a substrate through ubiquitin protea ...
Supervisor: Dawit Tekleyohans
Department: Molecular Biology, Laboratory of |
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Regeneration recalcitrance in plants
Regeneration recalcitrance is a problematic feature of several crop species, which prevents efficient scientific research in these crops. In this project you will attempt to obtain information on regeneration recalcitrance by usin ...
Supervisor: Janna Wittmer
Department: Molecular Biology, Laboratory of |
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The fountain of youth; Boosting plant regeneration using novel peptides.
The Netherlands is world leading in agriculture and plant breeding, but the current agricultural system has a substantial negative impact on our climate, demands enormous input of scarce resources, such as fresh water, nitrate, an ...
Supervisor: Dr. Martijn Fiers
Department: Molecular Biology, Laboratory of |
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