Project properties

Title Immune cell dynamics and mechanobiology
Group Cell Biology and Immunology Group
Project type thesis
Credits 12 BSc 36 MSc
Supervisor(s) Youri Peeters, Daan Vorselen
Examiner(s) Daan Vorselen
Contact info Bscthesis.cbi@wur.nl; mscthesis.cbi@wur.nl

Begin date 2024/01/01
End date 2024/12/31
Description Did you know that immune cells use physical forces to recognize and kill their prey? We try to understand how they do so, and reveal why softer prey, like cancer cells, evade immune recognition. Join us in our research where we develop synthetic targets to interrogate immune functions, and leverage advanced fluorescent microscopy and flow cytometry to see immune cells in action. Our main focus is macrophage biology and phagocytosis, but we are also excited about exploring how other immune cells use forces to kill!
Used skills Hydrogel synthesis and functionalization, advanced fluorescent microscopy, cell culturing, flow cytometry, biophysical methods (cellular force measurements)
Requirements recommended; CBI10306/CBI10806, CBI21303/CBI20803, CBI51303, BIP40306