Project properties

Title Comparative genomics and trait evolution of lettuce wild relatives
Group Biosystematics Group
Project type thesis
Credits 24-36
Supervisor(s) Prof. dr. Eric Schranz
Examiner(s) Prof. dr. M.Eric Schranz
Contact info eric.schranz@wur.nl
Begin date 2019/10/30
End date 2025/12/30
Description Description Establish a robust comparative genomics of cultivated lettuce with its wild relatives for trait and gene discovery which will benefit lettuce breeding. Lettuce breeding is faces many challenges related to pathogen resistance and climate change for which wild relatives provide important diversity. By combining the genomic data and advanced bioinformatics tools, following projects will be studied: (1) assemble and analyse the L. saligna genome (a source of non-host resistance) and diversity of additional lines from resequencing data; (2) assemble and analyse the L. virosa genome (a source of resistance to white flies and for drought tolerance) ) and diversity of additional lines from resequencing data; (3) identify key non-host resistance genes from L. saligna using transcriptomics and fine-mapping; and (4) establish a comparative genomics framework for Lactuca species and other sequenced Asteraceae species such as sunflower and dandelion.
Used skills qPCR, phylogenetics, bioinformatics, transcriptomics, gene family analysis, comparative genomics
Requirements